The Bavarians were desperate to bounce back from Saturday's 3-0 Bundesliga loss to leaders Bayer Leverkusen which left them five points off the top, but they will return to Munich with more pressure piling on head coach Thomas Tuchel after his side's second straight defeat.

Bayern have also now failed to score in their last two games but Tuchel, who struggled to explain his side's worrying form, played down concerns about his position after the match.

"Worried about my future? No, I am not," he said.

"We're frustrated and angry about the defeat. I think we lost the game, I'm not sure Lazio won it.

"I'm not sure why we lost our conviction in the second half, but we did, and then we fell behind. I can't explain it because we told the team to maintain their intensity and be even braver going forward, but we seemed to lose face at the start of the half.

"There are things we can build on. In the first half, we created some good chances, some big chances and one huge one with Jamal (Musiala), but in the end, we didn't have a single shot on target, so it's clear you can't win a game like that.

"But we've got a second leg and, obviously in conjunction with the last result, it doesn't look great, but we'll keep working hard."

Bayern started well as they pressed the Italians high and created chances for Joshua Kimmich, Harry Kane and Leroy Sane in the first half, who all narrowly missed the target.

Lazio, who had lost 6-2 on aggregate to Bayern at this stage three years ago, went close with a Luis Alberto shot that flew wide of Manuel Neuer's goal.

The tempo gradually dropped, Bayern struggled with the disciplined Italian back line and had to wait until the 40th minute to threaten again with Jamal Musiala firing over the bar from close range.

Lazio should have taken the lead two minutes after the restart when Isaksen only had Neuer to beat but the goalkeeper stood his ground to block his shot.

The Dane earned a penalty when Immobile passed to Isaksen in the box and Upamecano arrived late and stepped on his ankle.

Immobile kept his cool and sent Neuer the wrong way to give his team the advantage going into the return leg in Munich on March 5.