Triptans sold under brand names such as Imitrex, Zomig, Maxalt are the most effective in treating migraine attacks, according to a study published today in the online issue of Neurology.

Other classes of medications, such as ergots and anti-emetics, were found to be two to three times more effective than ibuprofen, which is sold under brand names such as Advil and Motrin.

Researchers looked at 25 medications among seven drug classes to determine which were most effective at treating migraine attacks compared to ibuprofen.

The scientists collected data over six years on more than 4.7 million treatment attempts by nearly 300,000 people via a smartphone app. The app collected information based on user input, frequency, triggers, symptoms, medication, and medication effectiveness.