President Joe Biden tested positive for COVID-19 while traveling Wednesday in Las Vegas and is experiencing “mild symptoms” including “general malaise” from the infection, the White House said.

Press secretary Karine Jean-Pierre said Biden will fly to his home in Delaware, where he will “self-isolate and will continue to carry out all of his duties fully during that time.” The news had first been shared by UnidosUS President and CEO Janet Murguía, who told guests at the group’s convention in Las Vegas that president had sent his regrets and could not appear because he tested positive for the virus.

Dr. Kevin O’Connor, the president’s physician, said in a note that Biden, 81, “presented this afternoon with upper respiratory symptoms, to include rhinorhea (runny nose) and non-productive cough, with general malaise.” After the positive COVID-19 test, Biden was prescribed the antiviral drug Paxlovid and has taken his first dose, O’Connor said.

Biden was slated to speak at the UnidosUS event in Las Vegas Wednesday afternoon as part of an effort to rally Hispanic voters ahead of the November election. Instead, he departed for the airport to fly to Delaware, where he had already been planning to spend a long weekend at his home in Rehoboth Beach.