Climate change is changing Earth in ways that are "unprecedented" in thousands of years — and in some cases, hundreds of thousands of years — according to a blistering report released Monday by the United Nations.

The sobering assessment also found that some changes that are already playing out, such as warming oceans and rising sea levels, are "irreversible for centuries to millennia."

The report is the most comprehensive assessment from the U.N.'s Intergovernmental Panel on Climate Change (IPCC) since 2013 and provides the strongest case yet for human-caused global warming, saying it's "unequivocal that human influence has warmed the atmosphere, ocean and land."

The report also found that climate change is intensifying, occurring at an accelerated pace and is already affecting every region of the planet.

"It has been clear for decades that the Earth's climate is changing, and the role of human influence on the climate system is undisputed," Valérie Masson-Delmotte, co-chair of the IPCC's Working Group I, said in a statement.

Ko Barrett, the IPCC’s vice- chair and a senior climate adviser at the National Oceanic and Atmospheric Administration, told NBC News that the report shows that no matter what humans do going forward, the future will be hotter than it is now.

“It can be kind of demoralizing or depressing to think that there are so many things that are kind of irreversible for a long period of time,” Barrett said. “But the good news is that, that these irreversible changes can be slowed down with rapid, strong and sustained reductions in greenhouse gas emissions.”

The IPCC, established in the late 1980s, consists of thousands of scientists across 195 member governments who pore over the most recent published and peer-reviewed research on global warming and compile the findings into a report on the current state of the climate. The assessment, which includes a look at the future risks and impacts of climate change, typically represents consensus within the scientific community. More than 230 authors contributed to the latest report.

The assessment comes less than three months before world leaders are set to convene from Oct. 31 to Nov. 12 in Glasgow, Scotland, for the 2021 U.N. Climate Change Conference. Countries are expected to set forth ambitious targets to reduce emissions by 2030, and the IPCC's findings will likely feature prominently in the discussions.

The report states that greenhouse gas emissions from human activities have caused global warming at a rate not seen in at least the past 2,000 years. It's estimated that human-caused climate change is responsible for approximately 1.1 degrees Celsius of warming since 1850-1900, the earliest period with reliable measurements of global surface temperatures, the authors wrote.

What's more, the report found that global temperatures are expected to exceed 2 degrees Celsius of warming this century "unless deep reductions in [carbon dioxide] and other greenhouse gas emissions occur in the coming decades."

"This report is a reality check," Masson-Delmotte said in the statement. "We now have a much clearer picture of the past, present and future climate, which is essential for understanding where we are headed, what can be done, and how we can prepare."

Climate scientists have warned that the increase in average global temperatures should be limited to under 2 degrees Celsius in order to avoid the most devastating effects of global warming. The 2-degree benchmark was set by climate negotiators in Copenhagen in 2009, but studies have increasingly found that the target may already be out of reach.

The new IPCC assessment goes further than any of the group's previous reports in linking human-caused climate change with increases in extreme weather events around the world.

"It is virtually certain that hot extremes (including heat waves) have become more frequent and more intense across most land regions since the 1950s, while cold extremes (including cold waves) have become less frequent and less severe," the authors wrote, adding that human-caused global warming is the "main driver" of those changes.

The report also details how the increasing ocean and surface temperatures will cause myriad physical changes in climate — including drought, heat waves, heavy rainfall and coastal flooding — in different regions of the planet.

The assessment is part of the IPCC's latest summary on climate change, called the Sixth Assessment Report or AR6, that will be published next year. The full report consists of four sections: the Working Group I report on the science of climate change; the Working Group II report on the vulnerabilities and socioeconomic impacts; the Working Group III report on possible ways to mitigate climate change; and the Synthesis Report, which reviews the findings from all the working groups and integrates relevant information for policymakers.