Source : Medical News Today
In leukemia, abnormal white blood cells (WBCs) grow and divide uncontrollably, replacing typical WBCs. This can have wide-reaching effects on the body.
Leukemia is a type of cancer that causes the bone marrow to produce abnormal blood cells. The disease can affect any type of blood cell, but most commonly affects WBCs that help protect against infection and illness.
This article outlines the various ways in which leukemia may affect the body, as well as a person’s day-to-day life. We also describe what leukemia is, including the different types.
How does leukemia affect the blood?
Leukemia leads to the rapid and significant production of abnormal blood cells, typically WBCs.
An excess of abnormal blood cells makes it more difficult for the bone marrow to produce other critical types of blood cells, such as red blood cells and platelets. This lack of red blood cells or platelets can lead to body aches and symptoms of anemia, or severe bruising and bleeding.
How does leukemia affect the bones?
A person may experience bone pain as their bone marrow becomes overcrowded by the growth of cancer cells. People most often feel this pain in the long bones of the legs and arms, or in the ribs and sternum.
Sometimes, a person may experience pain due to a mass of cancer cells forming near the nerves of the spinal cord.
Rarely, leukemia may weaken bones to the extent of causing bone fractures. This is more common in weight bearing bones, such as the:
How does leukemia affect the immune system?
WBCs play an essentialTrusted Source role in the function of the immune system. They are responsible for fighting infections and diseases in the body.
Leukemia typically affects WBCs, causing the bone marrow to produce abnormal WBCs that cannot fight infections as they should. This impairs the immune system, putting the body at increased risk of developing severe infections and illnesses.
How does leukemia affect the heart and muscles?
In leukemia, it is possible for cancer cells to infiltrate blood vessels, causing issues such as ischemic cardiac disease, which is also called coronary artery disease (CAD). This is where the heart does not receive an adequate supply of blood and oxygen.
Additionally, certain medications used to treat leukemia may increase the risk of heart failure. Drugs called anthracyclines are the standard therapy for acute types of leukemia. These types progress rapidly, so they require more aggressive treatment. However, receiving high doses of anthracyclines over a short period increases their toxicity.
Muscle weakness is another condition that can affect people with leukemia. Unfortunately, it is often one of the earliest contributorsTrusted Source to poor quality of life in children with leukemia.
How does leukemia affect the digestive system?
Some forms of leukemia can affect the digestive system, although this is rare. For example, chronic lymphocytic leukemia affects the digestive system in about 5.7–13% of cases. Doctors refer to this as Richter’s syndrome.
Leukemic lesions or injuries can form in the stomach, ileum, and proximal colon. These conditions can become extremely serious or life threatening due toTrusted Source infection, bleeding, or inflammation of the intestinal tissues.
Leukemia and daily life
Leukemia and its treatment can affect a person’s physical and mental health. Many people with leukemia find it beneficial to seek practical or emotional support from a support group. Support can also come from friends and family and is an integral part of improving the person’s quality of life.
Below are some tips for dealing with the challenges that leukemia can present.
Managing fatigue
People with leukemia commonly experience extreme fatigue that affects their ability to perform regular everyday activities. The following may help a person to cope:
being flexible with plans
setting priorities on tasks
asking for help
managing nutrition
improving sleep habits
engaging in light activity, such as walking or gardening
Managing infection risk
People with leukemia may experience low WBC counts that make them more susceptible to infections. Some ways to limit the risk of infection include:
washing and sanitizing hands frequently
avoiding people who are sick
staying away from crowded places
Managing side effects of treatment
Although necessary, leukemia treatment may cause side effects. One primary treatment for leukemia is chemotherapy, which may cause:
loss of appetite
mouth sores
hair loss
diarrhea
constipation
nausea and vomiting
Doctors can prescribe medications to prevent or reduce some of the above symptoms, suggest self-management strategies, or provide referrals to other doctors to address symptoms and side effects.